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Clonazepam is an anti-anxiety medication in the
benzodiazepine family. The benzodiazepine family includes diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), flurazepam
(Dalmane), and others. Clonazepam and other benzodiazepines act by enhancing the
effects of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter
which inhibits many of the activities of the brain. It is believed that excessive activity in the brain
may lead to anxiety or other psychiatric disorders. Clonazepam also is used to prevent
certain types of seizures.
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The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Clonazepam is used for the short-term relief of the symptoms of anxiety. It is used for certain types of seizures, specifically petit mal seizures, akinetic seizures, and myoclonus, as well as Lennox-Gastaut syndrome. For these seizure disorders, clonazepam may use alone or together with other medications.
Clonazepam comes as a tablet to take by mouth. Clonazepam usually is taken three times a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Clonazepam exactly as directed. Clonazepam can be habit-forming. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tolerance may develop with long-term or excessive use, making the drug less effective. Clonazepam must be taken regularly to be effective. Do not skip doses even if you feel that you do not need them. Do not take clonazepam for more than 4 months or stop taking Clonazepam without talking to your doctor. Stopping the drug suddenly can worsen your condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability). Your doctor will most likely decrease your dose gradually.
The most commonly noted side effects associated with clonazepam are sedation, which is reported in approximately 1 in 2 people (one-half of patients), dizziness (one-third of patients), weakness, and unsteadiness. Other side effects include a feeling of depression, loss of orientation, headache, and sleep disturbance.
Clonazepam and other benzodiazepines have been associated with fetal damage, including congenital malformations, when taken by pregnant women in their first trimester. Clonazepam is best avoided in the first trimester, and probably throughout pregnancy.It is not known if clonazepam is secreted in breast milk. Like all benzodiazepines, clonazepam can cause physical dependence. Suddenly stopping therapy after a few months of daily therapy may be associated with a feeling of loss of self-worth, agitation, and insomnia. If clonazepam is taken continuously for longer than a few months, stopping therapy suddenly may produce seizures, tremors, muscle cramping, vomiting, and/or sweating. Therefore, discontinuation usually is accomplished by tapering the dose.
Clonazepam, and all benzodiazepines, interact with other medications and drugs that slow the brain's processes, such as alcohol, barbiturates, and narcotics.
Take any missed dose of Clonazepam as soon as possible but not if it is almost time for the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose of Clonazepam. If more than one dose of Clonazepam is missed, contact your doctor or pharmacist to establish a new dosing schedule.
If overdose of Clonazepam is suspected, contact your local poison control center or emergency room immediately.
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